Johnes disease in cattle is an infectious disease of the
intestinal tract caused by a bacterium called Mycobacterium avium subspecies
paratuberculosis. This particular disease has received increasing attention by cattle
associations and veterinarians because the bacteria or genetic components of it have been
detected in humans with Crohns disease. Crohns disease in humans is a chronic
intestinal disease in people over 15 years old that has no established cause or cure and
it resembles the disease in cattle. The significance of these findings in humans as they
relate to Crohns disease are unknown at this time.
Cattle may be infected with the bacteria; thus, their feces may pose a
threat to human safety. Producers should practice good manure management practices to
prevent manure and winter run-off from entering watercourses. Composted manure should be
used as a fertilizer on vegetable and fruit crops rather than fresh manure. Drinking water
for human consumption should be filtered and chlorinated.
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Johnes disease is a herd problem
because when one animal shows clinical signs in a herd, then probably more animals are
infected.
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Animals most commonly affected are
cattle, sheep, and goats. However, Johnes disease has also been reported in deer,
elk, and antelope, as well as a few isolated cases in pigs, horses, chickens, llamas, and
nonhuman primates.
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The disease generally enters a herd when
an infected, healthy animal enters.
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The manure of infected animals is the
most common source of infection to other animals, and clinically infected animals shed
high numbers of organisms. The organisms dont multiple in the environment but they
can survive for over a year because of their resistance to heat, cold, and drying.
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Animals become infected most commonly by
ingestion of the bacteria, through sucking on manure-contaminated teats, licking
contaminated equipment, consuming manure contaminated feed or drinking water. Transmission
of the bacteria is also possible through the colostrum and milk of infected cows.
Occasionally a fetus may become infected if the mother is in the later stages of disease.
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Usually, clinical signs of disease are
not obvious until the animal is mature (3-6 years of age), even though infection usually
occurred during the first few months of life. Cattle become more resistant to infection
with age.
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Cattle with Johnes disease have a
long-lasting diarrhea and lose weight, despite a good appetite. Some infected animals are
unthrifty and weak and may have bottle jaw (fluid under the jaw), whereas, others just
have a chronic diarrhea. Signs of disease may occur within a few weeks after a stressful
event, such as calving.
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The disease may be recognized in a herd
by: 1) clinical signs of weight loss and chronic diarrhea in cows with a good appetite, 2)
a history of low herd production, and 3) culture of the organisms in the feces, blood, or
colostrum (success of culture depends on animals age and stage of infection).
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Currently, there is no treatment in
cattle that will cure infected or sick animals.
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Currently, there is no vaccine available
in Canada that prevents Johnes infection.
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Johnes disease can be prevented,
controlled and even eliminated in infected herds by applying critical management points
that are based on the understanding of the disease. A typical herd control program may
take 5 years or longer.
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Prevent infections by acquiring cattle
from test-negative herds or pre-testing mature cow additions.
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Control Johnes disease by manure
management.
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Provide clean water by using water
troughs or restricted access to waterways.
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Provide clean feed by feeding off of the
ground.
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Divert manure runoff from water sources.
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Provide clean, well-bedded, and spacious
calving areas. Move cow/calf pairs to a clean nursing area as soon as possible. Have
separate calving and hospital areas.
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Remove newborn calves from infected dams.
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Feed colostrum from negative cows.
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Cull clinically infected animals as soon
as possible and segregate them from others until they are culled.
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Carry out a testing strategy i.e. at
pregnancy exam or vaccination time, to identify subclinically infected animals, and then
cull, segregate, or manage them to reduce exposure to others.
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Transport cattle in clean livestock
trucks.
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Contact your herd veterinarian for more
information.
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